Generation of HEXA-deficient hiPSCs from fibroblasts of a Tay

Human iPSC line TSD-01-hiPSC was generated from fibroblasts of a patient with infantile Tay-Sachs disease (TSD). The patient is compound heterozygous …

Presynaptic Dysfunction in Neurons Derived from Tay–Sachs iPSCs - ScienceDirect

Tay-Sachs disease, illustration - Stock Image - F034/4334 - Science Photo Library

Pharmacological Enhancement of β-Hexosaminidase Activity in Fibroblasts from Adult Tay-Sachs and Sandhoff Patients - ScienceDirect

Frontiers Therapeutic Strategies For Tay-Sachs Disease

The C-Mannosylome of Human Induced Pluripotent Stem Cells Implies a Role for ADAMTS16 C-Mannosylation in Eye Development - ScienceDirect

Hexosaminidase a deficiency hi-res stock photography and images - Alamy

Engineering of Human-Induced Pluripotent Stem Cells for Precise Disease Modeling

iPSCs for modeling lysosomal storage diseases - ScienceDirect

Modeling neuronopathic storage diseases with patient-derived culture systems. - Abstract - Europe PMC

Frontiers Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis