Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors as Therapeutic Agents for Acute Leukemia

A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1, Cancer Cell International

Covalent and noncovalent constraints yield a figure eight-like conformation of a peptide inhibiting the menin-MLL interaction - ScienceDirect

Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors as Therapeutic Agents for Acute Leukemia

Therapeutic implications of menin inhibition in acute leukemias

Cancers, Free Full-Text

PDF] Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.

Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors as Therapeutic Agents for Acute Leukemia

A Box of Chemistry to Inhibit the MEN1 Tumor Suppressor Gene Promoting Leukemia - Ozyerli‐Goknar - 2021 - ChemMedChem - Wiley Online Library

Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair, Clinical Epigenetics

Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors as Therapeutic Agents for Acute Leukemia

Cancers, Free Full-Text

Challenges and opportunities in targeting the menin-MLL interaction.